| 1. Round | 21/08/2021 | Stade Rennais [Youth] | - | USSA Vertou [Youth] | 2:1 | ||||
| 2. Round | 29/08/2021 | USSA Vertou [Youth] | - | Stade Brestois 29 [Youth] | 1:1 | ||||
| 3. Round | 05/09/2021 | EA Guingamp [Youth] | - | USSA Vertou [Youth] | 2:0 | ||||
| 4. Round | 12/09/2021 | USSA Vertou [Youth] | - | Le Mans FC [Youth] | 0:1 | ||||
| 5. Round | 19/09/2021 | SA Mérignac [Youth] | - | USSA Vertou [Youth] | 3:1 | ||||
| 6. Round | 26/09/2021 | Tours FC [Youth] | - | USSA Vertou [Youth] | 0:3 |  |
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| 7. Round | 03/10/2021 | USSA Vertou [Youth] | - | Girondins Bordeaux [Youth] | 0:0 | ||||
| 8. Round | 09/10/2021 | FC Nantes [Youth] | - | USSA Vertou [Youth] | 3:1 | ||||
| 9. Round | 17/10/2021 | USSA Vertou [Youth] | - | Angers SCO [Youth] | 1:1 | ||||
| 10. Round | 24/10/2021 | LB Châteauroux [Youth] | - | USSA Vertou [Youth] | 0:1 | ||||
| 12. Round | 21/11/2021 | US Concarneau [Youth] | - | USSA Vertou [Youth] | 2:1 | ||||
| 13. Round | 28/11/2021 | USSA Vertou [Youth] | - | Stade Lavallois [Youth] | 2:2 | ||||
| 14. Round | 05/12/2021 | Stade Brestois 29 [Youth] | - | USSA Vertou [Youth] | 5:0 |
France