| 13. Round | 24/02/2021 | FC Differdange 03 | - | Union Titus Pétange | 2:2 | ||||
| 14. Round | 28/02/2021 | Progrès Niedercorn | - | FC Differdange 03 | 1:1 | ||||
| 11. Round | 10/03/2021 | FC Differdange 03 | - | F91 Dudelange | 1:0 | ||||
| 17. Round | 21/03/2021 | FC Differdange 03 | - | US Mondorf | 1:2 | ||||
| 18. Round | 28/03/2021 | Etzella Ettelbruck | - | FC Differdange 03 | 0:3 |  |
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| 19. Round | 05/04/2021 | FC Differdange 03 | - | US Hostert | 0:1 | ||||
| 25. Round | 02/05/2021 | F91 Dudelange | - | FC Differdange 03 | 3:1 | ||||
| 26. Round | 09/05/2021 | FC Differdange 03 | - | RM Hamm Benfica | 3:0 | ||||
| 27. Round | 12/05/2021 | Union Titus Pétange | - | FC Differdange 03 | 0:2 | ||||
| 21. Round | 19/05/2021 | FC Wiltz 71 | - | FC Differdange 03 | 0:2 | ||||
| 29. Round | 22/05/2021 | CS FOLA Esch | - | FC Differdange 03 | 5:0 | ||||
| 30. Round | 30/05/2021 | FC Differdange 03 | - | Swift Hesperange | 3:1 |
Cameroon