| 2. Round | 14/08/2021 | GFA Rumilly Vallières | - | Marignane Gignac FC | 1:1 | ||||
| 3. Round | 21/08/2021 | Marignane Gignac FC | - | AS Saint-Priest | 0:1 | ||||
| 4. Round | 28/08/2021 | Étoile FC | - | Marignane Gignac FC | 2:0 |  |
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| 6. Round | 11/09/2021 | Aubagne FC | - | Marignane Gignac FC | 3:0 | ||||
| 7. Round | 18/09/2021 | Marignane Gignac FC | - | Jura Sud | 1:0 | |
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| 8. Round | 25/09/2021 | Olympique Marseille B | - | Marignane Gignac FC | 2:3 | ||||
| 9. Round | 09/10/2021 | Marignane Gignac FC | - | SC Toulon | 0:1 | ||||
| 10. Round | 23/10/2021 | Marignane Gignac FC | - | Olympique Lyonnais B | 4:0 |
France