| 2. Round | 14/08/2021 | FC Martigues | - | Olympique Lyonnais B | 1:1 | ||||
| 3. Round | 21/08/2021 | RC Grasse | - | FC Martigues | 0:0 | ||||
| 4. Round | 28/08/2021 | FC Martigues | - | Louhans-Cuiseaux | 1:1 | ||||
| 10. Round | 23/10/2021 | AS Saint-Priest | - | FC Martigues | 1:1 | ||||
| 12. Round | 20/11/2021 | GOAL FC | - | FC Martigues | 1:1 | ||||
| 14. Round | 11/12/2021 | Jura Sud | - | FC Martigues | 1:4 | ||||
| 1. Round | 18/12/2021 | Marignane Gignac FC | - | FC Martigues | 1:1 | ||||
| 17. Round | 05/02/2022 | FC Martigues | - | RC Grasse | 2:0 |  |
|||
| 19. Round | 19/02/2022 | FC Martigues | - | Hyères FC | 3:1 |  |
|||
| 18. Round | 26/02/2022 | Louhans-Cuiseaux | - | FC Martigues | 0:2 | |
|||
| 20. Round | 05/03/2022 | Lyon-La Duchère | - | FC Martigues | 2:2 | |
|||
| 21. Round | 12/03/2022 | FC Martigues | - | AS Monaco B | 1:2 | |
|||
| 28. Round | 14/05/2022 | FC Martigues | - | Jura Sud | 3:1 | ||||
| 30. Round | 28/05/2022 | FC Martigues | - | Marignane Gignac FC | 3:0 |
France