| 1. Round | 13/02/2022 | Platense | - | Talleres de Córdoba | 1:0 | ||||
| 3. Round | 20/02/2022 | Platense | - | Sarmiento de Junín | 2:0 | ||||
| 4. Round | 26/02/2022 | Platense | - | Banfield | 0:1 | ||||
| 5. Round | 04/03/2022 | Unión de Santa Fe | - | Platense | 1:0 | ||||
| 6. Round | 12/03/2022 | Platense | - | Patronato de Paraná | 1:2 |  |
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| 9. Round | 10/04/2022 | Platense | - | Racing Club | 0:1 | |
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| 10. Round | 16/04/2022 | San Lorenzo | - | Platense | 2:2 | ||||
| 11. Round | 20/04/2022 | Platense | - | Gimnasia de La Plata | 0:3 | ||||
| 13. Round | 03/05/2022 | Platense | - | Argentinos Juniors | 1:1 | ||||
| 14. Round | 09/05/2022 | River Plate | - | Platense | 2:1 |
Argentina
Italy