| 12. Round | 17/10/2005 | Stade Brestois 29 | - | EA Guingamp | 2:1 | ||||
| 20. Round | 03/01/2006 | EA Guingamp | - | FC Istres | 2:0 | ||||
| 21. Round | 10/01/2006 | FC Lorient | - | EA Guingamp | 2:1 | ||||
| 22. Round | 13/01/2006 | EA Guingamp | - | Dijon FCO | 0:0 | ||||
| 36. Round | 28/04/2006 | Clermont Foot Auvergne | - | EA Guingamp | 3:2 |  |
France