| 2. Round | 15/02/2022 | Defensa y Justicia II | - | Racing Club II | 1:0 | ||||
| 3. Round | 19/02/2022 | Racing Club II | - | Argentinos Juniors II | 0:4 | ||||
| 4. Round | 24/02/2022 | River Plate II | - | Racing Club II | 4:2 |  |
|||
| 5. Round | 06/03/2022 | Racing Club II | - | Talleres de Córdoba II | 1:2 | ||||
| 6. Round | 14/03/2022 | Atlético Tucumán II | - | Racing Club II | 2:6 | |
|||
| 7. Round | 22/03/2022 | Independiente II | - | Racing Club II | 2:0 | ||||
| 9. Round | 08/04/2022 | Platense II | - | Racing Club II | 1:0 | ||||
| 10. Round | 15/04/2022 | Racing Club II | - | Unión de Santa Fe II | 2:0 | ||||
| 11. Round | 20/04/2022 | Patronato de Paraná II | - | Racing Club II | 3:1 | ||||
| 12. Round | 26/04/2022 | Racing Club II | - | Newell's Old Boys II | 1:1 | ||||
| 13. Round | 02/05/2022 | Racing Club II | - | Banfield II | 2:0 | ||||
| 14. Round | 09/05/2022 | San Lorenzo II | - | Racing Club II | 3:1 |
Argentina
Paraguay