| Group F | 22/10/2020 | SSC Napoli | - | AZ Alkmaar | 0:1 | ||||
| Group F | 29/10/2020 | Real Sociedad | - | SSC Napoli | 0:1 | ||||
| Group F | 05/11/2020 | HNK Rijeka | - | SSC Napoli | 1:2 | ||||
| Group F | 26/11/2020 | SSC Napoli | - | HNK Rijeka | 2:0 | ||||
| Group F | 03/12/2020 | AZ Alkmaar | - | SSC Napoli | 1:1 | ||||
| Group F | 10/12/2020 | SSC Napoli | - | Real Sociedad | 1:1 | ||||
| Round of 32 | 18/02/2021 | Granada CF | - | SSC Napoli | 2:0 | ||||
| Round of 32 | 25/02/2021 | SSC Napoli | - | Granada CF | 2:1 |  |
Serbia