| 12. Round | 20/11/2021 | Lille OSC [Youth] | - | US Orléans [Youth] | 1:4 | ||||
| 15. Round | 16/01/2022 | US Orléans [Youth] | - | Paris Saint-Germain [Youth] | 0:2 | ||||
| 16. Round | 23/01/2022 | Havre AC [Youth] | - | US Orléans [Youth] | 1:1 | ||||
| 17. Round | 06/02/2022 | US Orléans [Youth] | - | SM Caen [Youth] | 1:2 | ||||
| 18. Round | 12/02/2022 | FC Chambly [Youth] | - | US Orléans [Youth] | 0:2 | ||||
| 23. Round | 26/02/2022 | St-Pryvé St-Hilaire [Youth] | - | US Orléans [Youth] | 0:0 | ||||
| 19. Round | 05/03/2022 | US Orléans [Youth] | - | Valenciennes FC [Youth] | 0:2 | ||||
| 24. Round | 17/04/2022 | US Orléans [Youth] | - | Lille OSC [Youth] | 4:2 | ||||
| 25. Round | 01/05/2022 | Entente Feignies Aulnoye [Youth] | - | US Orléans [Youth] | 1:1 |
France