| 4. Round | 12/09/2021 | FC Nantes [Youth] | - | Stade Brestois 29 [Youth] | 1:3 | ||||
| 5. Round | 19/09/2021 | Stade Brestois 29 [Youth] | - | Angers SCO [Youth] | 2:2 | ||||
| 8. Round | 10/10/2021 | US Concarneau [Youth] | - | Stade Brestois 29 [Youth] | 3:4 | ||||
| 9. Round | 16/10/2021 | Stade Brestois 29 [Youth] | - | Stade Lavallois [Youth] | 3:2 | ||||
| 15. Round | 16/01/2022 | Girondins Bordeaux [Youth] | - | Stade Brestois 29 [Youth] | 1:2 | ||||
| 21. Round | 13/02/2022 | Stade Brestois 29 [Youth] | - | LB Châteauroux [Youth] | 1:0 | ||||
| 19. Round | 02/04/2022 | Stade Brestois 29 [Youth] | - | Stade Rennais [Youth] | 1:1 | ||||
| 23. Round | 10/04/2022 | Tours FC [Youth] | - | Stade Brestois 29 [Youth] | 0:0 |
France