| 2. Round | 12/09/2021 | Valencia CF [Women] | - | Sporting de Huelva [Women] | 2:2 | ||||
| 4. Round | 29/09/2021 | Valencia CF [Women] | - | Athletic Club [Women] | 1:3 | ||||
| 5. Round | 03/10/2021 | Valencia CF [Women] | - | Sevilla FC [Women] | 1:2 | ||||
| 11. Round | 21/11/2021 | Valencia CF [Women] | - | Real Betis [Women] | 1:0 | ||||
| 12. Round | 05/12/2021 | CD Alavés [Women] | - | Valencia CF [Women] | 3:1 | ||||
| 13. Round | 12/12/2021 | Valencia CF [Women] | - | Madrid CFF [Women] | 1:3 | ||||
| 14. Round | 18/12/2021 | Villarreal CF [Women] | - | Valencia CF [Women] | 0:2 | ||||
| 15. Round | 22/12/2021 | Valencia CF [Women] | - | SD Eibar [Women] | 2:0 | ||||
| 16. Round | 09/01/2022 | Sporting de Huelva [Women] | - | Valencia CF [Women] | 2:0 | ||||
| 17. Round | 12/01/2022 | Valencia CF [Women] | - | Real Sociedad [Women] | 0:3 | ||||
| 18. Round | 16/01/2022 | Sevilla FC [Women] | - | Valencia CF [Women] | 3:1 | ||||
| 30. Round | 15/05/2022 | SD Eibar [Women] | - | Valencia CF [Women] | 5:1 |
Spain