| 2. Round | 16/01/2021 | Atlas Guadalajara [Women] | - | UANL Tigres [Women] | 2:1 | ||||
| 3. Round | 26/01/2021 | Club Tijuana [Women] | - | Atlas Guadalajara [Women] | 0:1 | ||||
| 5. Round | 04/02/2021 | Atlas Guadalajara [Women] | - | CF Pachuca [Women] | 3:3 | ||||
| 6. Round | 07/02/2021 | Puebla FC [Women] | - | Atlas Guadalajara [Women] | 0:1 | ||||
| 7. Round | 13/02/2021 | Atlas Guadalajara [Women] | - | Santos Laguna [Women] | 3:2 | ||||
| 8. Round | 27/02/2021 | Mazatlán FC [Women] | - | Atlas Guadalajara [Women] | 2:2 | ||||
| 11. Round | 14/03/2021 | Atlas Guadalajara [Women] | - | Deportivo Guadalajara [Women] | 3:3 | ||||
| 12. Round | 19/03/2021 | Gallos Blancos [Women] | - | Atlas Guadalajara [Women] | 0:1 | ||||
| 13. Round | 27/03/2021 | Atlas Guadalajara [Women] | - | Deportivo Toluca [Women] | 1:2 |  |
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| 14. Round | 02/04/2021 | Atlético San Luis [Women] | - | Atlas Guadalajara [Women] | 1:2 |
Mexico