 |
 |
|
|
| 18/03/2021 | 16:00 | Cruz Azul | - | Mazatlán FC | 3:0 (2:0) | |
| 19/03/2021 | 23:00 | Gallos Blancos | - | Atlas Guadalajara | 0:1 (0:0) | |
| 20/03/2021 | 18:00 | Pumas UNAM | - | Club León | 2:0 (2:0) | |
| 21/03/2021 | 16:00 | Deportivo Guadalajara | - | Puebla FC | 3:0 (2:0) | |
| 23:00 | Atlético San Luis | - | Santos Laguna | 2:2 (0:0) | ||
| 22/03/2021 | 18:00 | Deportivo Toluca | - | Club Necaxa | 1:1 (1:0) | |
| 23/03/2021 | 01:00 | CF Pachuca | - | CF América | 0:0 (0:0) | |
| 02:30 | UANL Tigres | - | FC Juárez | 3:0 (0:0) | ||
| 03:00 | Club Tijuana | - | CF Monterrey | 0:2 (0:2) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
UANL Tigres | 12 | 9 | 2 | 1 | 27:5 | 22 | 29 |
| 2 |
|
Atlas Guadalajara | 12 | 8 | 3 | 1 | 22:15 | 7 | 27 |
| 3 |
|
CF Monterrey | 12 | 8 | 1 | 3 | 31:11 | 20 | 25 |
| 4 |
|
Deportivo Guadalajara | 12 | 7 | 3 | 2 | 27:12 | 15 | 24 |
| 5 |
|
Pumas UNAM | 12 | 7 | 3 | 2 | 18:10 | 8 | 24 |
| 6 |
|
Cruz Azul | 12 | 6 | 4 | 2 | 17:13 | 4 | 22 |
| 7 |
|
CF Pachuca | 12 | 5 | 3 | 4 | 15:12 | 3 | 18 |
| 8 |
|
CF América | 12 | 4 | 5 | 3 | 16:14 | 2 | 17 |
| 9 |
|
Deportivo Toluca | 12 | 4 | 5 | 3 | 11:11 | 0 | 17 |
| 10 |
|
Mazatlán FC | 12 | 4 | 4 | 4 | 12:17 | -5 | 16 |
| 11 |
|
Club Tijuana | 12 | 4 | 3 | 5 | 11:13 | -2 | 15 |
| 12 |
|
Santos Laguna | 12 | 2 | 5 | 5 | 15:21 | -6 | 11 |
| 13 |
|
Gallos Blancos | 12 | 3 | 1 | 8 | 11:19 | -8 | 10 |
| 14 |
|
Atlético San Luis | 12 | 2 | 4 | 6 | 13:24 | -11 | 10 |
| 15 |
|
Club Necaxa | 12 | 2 | 3 | 7 | 9:22 | -13 | 9 |
| 16 |
|
Club León | 12 | 2 | 2 | 8 | 9:26 | -17 | 8 |
| 17 |
|
Puebla FC | 12 | 1 | 4 | 7 | 8:17 | -9 | 7 |
| 18 |
|
FC Juárez | 12 | 1 | 3 | 8 | 10:20 | -10 | 6 |
| Playoffs |
