 |
 |
|
|
| 26/03/2021 | 22:00 | Club Necaxa | - | Atlético San Luis | 1:1 (1:0) | |
| 27/03/2021 | 01:00 | Mazatlán FC | - | Pumas UNAM | 0:0 (0:0) | |
| 16:00 | Atlas Guadalajara | - | Deportivo Toluca | 1:2 (1:2) | ||
| 28/03/2021 | 03:05 | CF América | - | Deportivo Guadalajara | 2:4 (1:2) | |
| 19:00 | Puebla FC | - | CF Pachuca | 0:1 (0:0) | ||
| 29/03/2021 | 04:00 | FC Juárez | - | Gallos Blancos | 2:0 (1:0) | |
| 23:30 | Santos Laguna | - | Cruz Azul | 2:1 (1:0) | ||
| 30/03/2021 | 02:00 | Club León | - | Club Tijuana | 2:1 (1:0) | |
| 04:00 | CF Monterrey | - | UANL Tigres | 2:2 (1:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
UANL Tigres | 13 | 9 | 3 | 1 | 29:7 | 22 | 30 |
| 2 |
|
Deportivo Guadalajara | 13 | 8 | 3 | 2 | 31:14 | 17 | 27 |
| 3 |
|
Atlas Guadalajara | 13 | 8 | 3 | 2 | 23:17 | 6 | 27 |
| 4 |
|
CF Monterrey | 13 | 8 | 2 | 3 | 33:13 | 20 | 26 |
| 5 |
|
Pumas UNAM | 13 | 7 | 4 | 2 | 18:10 | 8 | 25 |
| 6 |
|
Cruz Azul | 13 | 6 | 4 | 3 | 18:15 | 3 | 22 |
| 7 |
|
CF Pachuca | 13 | 6 | 3 | 4 | 16:12 | 4 | 21 |
| 8 |
|
Deportivo Toluca | 13 | 5 | 5 | 3 | 13:12 | 1 | 20 |
| 9 |
|
CF América | 13 | 4 | 5 | 4 | 18:18 | 0 | 17 |
| 10 |
|
Mazatlán FC | 13 | 4 | 5 | 4 | 12:17 | -5 | 17 |
| 11 |
|
Club Tijuana | 13 | 4 | 3 | 6 | 12:15 | -3 | 15 |
| 12 |
|
Santos Laguna | 13 | 3 | 5 | 5 | 17:22 | -5 | 14 |
| 13 |
|
Atlético San Luis | 13 | 2 | 5 | 6 | 14:25 | -11 | 11 |
| 14 |
|
Club León | 13 | 3 | 2 | 8 | 11:27 | -16 | 11 |
| 15 |
|
Gallos Blancos | 13 | 3 | 1 | 9 | 11:21 | -10 | 10 |
| 16 |
|
Club Necaxa | 13 | 2 | 4 | 7 | 10:23 | -13 | 10 |
| 17 |
|
FC Juárez | 13 | 2 | 3 | 8 | 12:20 | -8 | 9 |
| 18 |
|
Puebla FC | 13 | 1 | 4 | 8 | 8:18 | -10 | 7 |
| Playoffs |
