| 1. Round | 13/12/2000 | Granada CF | - | Recreativo Huelva | 1:0 | ||||
| 2. Round | 02/01/2001 | Granada CF | - | Villarreal CF | 4:2 pso | ||||
| Round of 16 | 10/01/2001 | Guadix Club de Fútbol | - | Granada CF | 0:0 |  |
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| Round of 16 | 17/01/2001 | Granada CF | - | Guadix Club de Fútbol | 5:4 pso | |
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| Quarter-finals | 31/01/2001 | Granada CF | - | Atlético Madrid | 0:1 | |
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| Quarter-finals | 06/02/2001 | Atlético Madrid | - | Granada CF | 3:1 | |
Spain