| 12. Round | 20/11/2021 | Olympique Lyonnais B | - | RC Grasse | 1:0 | ||||
| 13. Round | 04/12/2021 | RC Grasse | - | SC Toulon | 2:1 | ||||
| 14. Round | 11/12/2021 | RC Grasse | - | Louhans-Cuiseaux | 0:0 | ||||
| 16. Round | 22/01/2022 | RC Grasse | - | AS Monaco B | 0:0 | ||||
| 15. Round | 29/01/2022 | Hyères FC | - | RC Grasse | 1:1 | ||||
| 17. Round | 05/02/2022 | FC Martigues | - | RC Grasse | 2:0 | ||||
| 24. Round | 09/04/2022 | RC Grasse | - | Olympique Marseille B | 3:1 | ||||
| 25. Round | 16/04/2022 | Marignane Gignac FC | - | RC Grasse | 1:2 | ||||
| 26. Round | 23/04/2022 | RC Grasse | - | Olympique Lyonnais B | 2:1 | ||||
| 27. Round | 30/04/2022 | SC Toulon | - | RC Grasse | 0:0 | ||||
| 28. Round | 14/05/2022 | Louhans-Cuiseaux | - | RC Grasse | 3:1 | ||||
| 30. Round | 28/05/2022 | Lyon-La Duchère | - | RC Grasse | 0:3 |  |
France