| 3. Round | 05/09/2021 | Olympique Marseille [Youth] | - | AS Béziers [Youth] | 5:1 | ||||
| 4. Round | 12/09/2021 | SC Toulon [Youth] | - | Olympique Marseille [Youth] | 0:1 | ||||
| 8. Round | 10/10/2021 | Olympique Marseille [Youth] | - | Toulouse FC [Youth] | 0:1 | ||||
| 10. Round | 24/10/2021 | Olympique Marseille [Youth] | - | Pieve di Lota [Youth] | 5:0 | ||||
| 12. Round | 21/11/2021 | Olympique Marseille [Youth] | - | US Colomiers [Youth] | 2:0 | ||||
| 14. Round | 05/12/2021 | Olympique Marseille [Youth] | - | Montpellier HSC [Youth] | 1:2 | ||||
| 16. Round | 30/01/2022 | Olympique Marseille [Youth] | - | SC Toulon [Youth] | 2:0 | ||||
| 19. Round | 06/03/2022 | Olympique Marseille [Youth] | - | OGC Nice [Youth] | 4:1 | ||||
| 20. Round | 20/03/2022 | Toulouse FC [Youth] | - | Olympique Marseille [Youth] | 0:0 | ||||
| 22. Round | 03/04/2022 | Pieve di Lota [Youth] | - | Olympique Marseille [Youth] | 0:7 |  |
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| 24. Round | 17/04/2022 | US Colomiers [Youth] | - | Olympique Marseille [Youth] | 1:1 | ||||
| 25. Round | 01/05/2022 | Olympique Marseille [Youth] | - | AC Ajaccio [Youth] | 1:2 | ||||
| 26. Round | 14/05/2022 | Nîmes Olympique [Youth] | - | Olympique Marseille [Youth] | 2:3 |
Algeria