| 1. Round | 28/08/2022 | Girondins Bordeaux [Youth B] | - | FC Istres [Youth B] | 1:1 | ||||
| 2. Round | 03/09/2022 | FC Istres [Youth B] | - | Olympique Marseille [Youth B] | 2:1 |  |
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| 10. Round | 06/11/2022 | FC Istres [Youth B] | - | SA Mérignac [Youth B] | 5:1 |  |
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| 11. Round | 12/11/2022 | Toulouse FC [Youth B] | - | FC Istres [Youth B] | 3:1 | ||||
| 12. Round | 20/11/2022 | Canet Roussillon [Youth B] | - | FC Istres [Youth B] | 1:2 | |
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| 13. Round | 27/11/2022 | FC Istres [Youth B] | - | AC Vedène [Youth B] | 1:0 | ||||
| 14. Round | 03/12/2022 | Olympique Marseille [Youth B] | - | FC Istres [Youth B] | 2:1 | |
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| 15. Round | 14/01/2023 | FC Istres [Youth B] | - | Montpellier HSC [Youth B] | 1:1 | ||||
| 16. Round | 22/01/2023 | JE Toulousaine [Youth B] | - | FC Istres [Youth B] | 2:5 | ||||
| 18. Round | 12/02/2023 | Marignane Gignac [Youth B] | - | FC Istres [Youth B] | 1:3 | ||||
| 17. Round | 18/02/2023 | FC Istres [Youth B] | - | Rodez AF [Youth B] | 2:0 | ||||
| 19. Round | 05/03/2023 | FC Istres [Youth B] | - | Balma SC [Youth B] | 3:1 |
Spain