| 2. Round | 29/08/2021 | US Colomiers [Youth] | - | Toulouse FC [Youth] | 1:1 | ||||
| 3. Round | 05/09/2021 | Toulouse FC [Youth] | - | AC Ajaccio [Youth] | 4:2 | ||||
| 4. Round | 12/09/2021 | Nîmes Olympique [Youth] | - | Toulouse FC [Youth] | 0:1 | ||||
| 5. Round | 19/09/2021 | Toulouse FC [Youth] | - | Montpellier HSC [Youth] | 2:0 | ||||
| 7. Round | 03/10/2021 | Toulouse FC [Youth] | - | SC Toulon [Youth] | 2:0 | ||||
| 9. Round | 17/10/2021 | Toulouse FC [Youth] | - | AS Cannes [Youth] | 0:2 |
France