| 6. Round | 16/09/2022 | Leeds United U21 | - | Southampton FC U21 | 6:2 | ||||
| 8. Round | 08/10/2022 | Southampton FC U21 | - | Aston Villa U21 | 2:0 | ||||
| 9. Round | 23/10/2022 | Newcastle United U21 | - | Southampton FC U21 | 3:2 | ||||
| 11. Round | 07/11/2022 | Sunderland AFC U21 | - | Southampton FC U21 | 1:3 | ||||
| 14. Round | 27/01/2023 | Middlesbrough FC U21 | - | Southampton FC U21 | 2:2 | ||||
| 15. Round | 10/02/2023 | Southampton FC U21 | - | Sunderland AFC U21 | 2:2 |  |
|||
| 16. Round | 20/02/2023 | West Bromwich Albion U21 | - | Southampton FC U21 | 1:2 | ||||
| 17. Round | 24/02/2023 | Southampton FC U21 | - | Leeds United U21 | 1:2 | ||||
| 19. Round | 17/03/2023 | Aston Villa U21 | - | Southampton FC U21 | 1:2 | ||||
| 5. Round | 31/03/2023 | Derby County U21 | - | Southampton FC U21 | 1:3 | |
|||
| 21. Round | 14/04/2023 | Southampton FC U21 | - | Stoke City U21 | 2:0 | ||||
| 22. Round | 23/04/2023 | Norwich City U21 | - | Southampton FC U21 | 2:5 | |
England
Ghana