| 9. Round | 09/10/2021 | RC Lens B | - | Stade de Reims B | 2:5 | ||||
| 10. Round | 23/10/2021 | AJ Auxerre B | - | RC Lens B | 1:1 | ||||
| 11. Round | 06/11/2021 | RC Lens B | - | FCSR Haguenau | 3:2 |  |
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| 12. Round | 20/11/2021 | Paris 13 Atletico | - | RC Lens B | 0:0 | ||||
| 14. Round | 11/12/2021 | Olympique Saint-Quentin | - | RC Lens B | 1:1 |  |
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| 17. Round | 05/02/2022 | FC Metz B | - | RC Lens B | 0:0 | ||||
| 19. Round | 19/02/2022 | Entente SSG | - | RC Lens B | 1:0 | |
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| 18. Round | 26/02/2022 | RC Lens B | - | SC Schiltigheim | 1:1 | ||||
| 20. Round | 05/03/2022 | RC Lens B | - | SAS Épinal | 0:1 | ||||
| 28. Round | 14/05/2022 | RC Lens B | - | Olympique Saint-Quentin | 1:2 | |
Mali
France