| 1. Round | 29/08/2021 | FC Mantois [Youth B] | - | Tours FC [Youth B] | 2:0 | ||||
| 12. Round | 28/11/2021 | US Avranches [Youth B] | - | Tours FC [Youth B] | 2:1 | ||||
| 13. Round | 05/12/2021 | Tours FC [Youth B] | - | CS Brétigny [Youth B] | 3:4 |  |
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| 14. Round | 16/01/2022 | Havre AC [Youth B] | - | Tours FC [Youth B] | 0:2 | ||||
| 16. Round | 06/02/2022 | Paris Saint-Germain [Youth B] | - | Tours FC [Youth B] | 9:1 | ||||
| 17. Round | 12/02/2022 | Tours FC [Youth B] | - | Le Mans FC [Youth B] | 1:4 | ||||
| 18. Round | 06/03/2022 | SM Caen [Youth B] | - | Tours FC [Youth B] | 3:2 | ||||
| 19. Round | 13/03/2022 | Tours FC [Youth B] | - | AS Vitré [Youth B] | 2:1 | ||||
| 20. Round | 20/03/2022 | FC Rouen 1899 [Youth B] | - | Tours FC [Youth B] | 2:1 |
France