| 1. Round | 28/08/2022 | Valenciennes FC [Youth B] | - | Lille OSC [Youth B] | 2:3 | ||||
| 2. Round | 04/09/2022 | Lille OSC [Youth B] | - | ESTAC Troyes [Youth B] | 0:2 | ||||
| 5. Round | 25/09/2022 | US Boulogne [Youth B] | - | Lille OSC [Youth B] | 2:2 | ||||
| 6. Round | 02/10/2022 | Lille OSC [Youth B] | - | USL Dunkerque [Youth B] | 5:0 | ||||
| 9. Round | 23/10/2022 | Lille OSC [Youth B] | - | Stade de Reims [Youth B] | 0:1 | ||||
| 10. Round | 06/11/2022 | JA Drancy [Youth B] | - | Lille OSC [Youth B] | 3:1 |  |
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| 12. Round | 20/11/2022 | RC Lens [Youth B] | - | Lille OSC [Youth B] | 1:1 | ||||
| 16. Round | 22/01/2023 | AS Jeunesse Aubervilliers [Youth B] | - | Lille OSC [Youth B] | 1:4 | ||||
| 17. Round | 05/02/2023 | Lille OSC [Youth B] | - | US Boulogne [Youth B] | 3:1 | ||||
| 18. Round | 12/02/2023 | USL Dunkerque [Youth B] | - | Lille OSC [Youth B] | 0:3 | ||||
| 19. Round | 05/03/2023 | Lille OSC [Youth B] | - | Montfermeil FC [Youth B] | 4:3 | ||||
| 20. Round | 12/03/2023 | Lille OSC [Youth B] | - | Paris 13 Atletico [Youth B] | 2:0 |  |
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| 23. Round | 16/04/2023 | US Torcy [Youth B] | - | Lille OSC [Youth B] | 0:1 | ||||
| 24. Round | 23/04/2023 | Lille OSC [Youth B] | - | RC Lens [Youth B] | 2:4 |
France