| 1. Round | 29/01/2012 | Colo-Colo | - | Deportes Iquique | 0:0 | ||||
| 2. Round | 05/02/2012 | Antofagasta | - | Deportes Iquique | 1:1 | ||||
| 3. Round | 10/02/2012 | Universidad de Chile | - | Deportes Iquique | 1:1 | ||||
| 4. Round | 18/02/2012 | Deportes Iquique | - | Rangers | 2:0 |  |
|||
| 5. Round | 25/02/2012 | Deportes Iquique | - | Huachipato | 1:0 | ||||
| 6. Round | 03/03/2012 | Deportes Iquique | - | Audax Italiano | 1:2 | |
|||
| 7. Round | 11/03/2012 | Cobresal | - | Deportes Iquique | 0:4 | ||||
| 8. Round | 17/03/2012 | Deportes Iquique | - | O'Higgins | 1:2 | |
|||
| 9. Round | 24/03/2012 | Universidad Católica | - | Deportes Iquique | 1:1 | ||||
| 10. Round | 31/03/2012 | Deportes Iquique | - | Universidad de Concepción | 2:0 | ||||
| 11. Round | 07/04/2012 | Deportes Iquique | - | La Serena | 3:1 | |
|||
| 13. Round | 21/04/2012 | Deportes Iquique | - | Unión La Calera | 3:3 | |
|||
| 14. Round | 28/04/2012 | Palestino | - | Deportes Iquique | 0:1 | |
|||
| 15. Round | 05/05/2012 | Deportes Iquique | - | Santiago Wanderers | 2:1 | ||||
| 16. Round | 12/05/2012 | Unión Española | - | Deportes Iquique | 1:2 |
Chile