| 14. Round | 16/01/2022 | Olympique Lyonnais [Youth B] | - | ASPTT Dijon [Youth B] | 0:0 | ||||
| 16. Round | 06/02/2022 | Olympique Lyonnais [Youth B] | - | Racing Besançon [Youth B] | 7:2 | ||||
| 17. Round | 13/02/2022 | AJ Auxerre [Youth B] | - | Olympique Lyonnais [Youth B] | 1:0 | ||||
| 18. Round | 06/03/2022 | Olympique Lyonnais [Youth B] | - | FC Metz [Youth B] | 2:1 | ||||
| 19. Round | 30/03/2022 | FC Lyon [Youth B] | - | Olympique Lyonnais [Youth B] | 0:1 | ||||
| 24. Round | 17/04/2022 | SAS Épinal [Youth B] | - | Olympique Lyonnais [Youth B] | 1:5 | ||||
| 23. Round | 20/04/2022 | Olympique Lyonnais [Youth B] | - | FC Mulhouse [Youth B] | 4:0 | ||||
| 25. Round | 01/05/2022 | Olympique Lyonnais [Youth B] | - | AS Nancy Lorraine [Youth B] | 4:2 | ||||
| 26. Round | 15/05/2022 | RC Strasbourg [Youth B] | - | Olympique Lyonnais [Youth B] | 1:3 |
France
Algeria