| 5. Round | 27/08/1999 | FC Nantes | - | Montpellier HSC | 3:0 | ||||
| 6. Round | 10/09/1999 | Montpellier HSC | - | Olympique Marseille | 3:1 | ||||
| 7. Round | 18/09/1999 | AS Nancy Lorraine | - | Montpellier HSC | 1:2 | ||||
| 8. Round | 24/09/1999 | Montpellier HSC | - | CS Sedan | 1:1 | ||||
| 9. Round | 01/10/1999 | Havre AC | - | Montpellier HSC | 2:1 | ||||
| 10. Round | 12/10/1999 | Montpellier HSC | - | AS Saint-Étienne | 0:1 | ||||
| 11. Round | 15/10/1999 | RC Lens | - | Montpellier HSC | 1:0 | ||||
| 12. Round | 23/10/1999 | Montpellier HSC | - | SC Bastia | 1:1 | ||||
| 13. Round | 29/10/1999 | AJ Auxerre | - | Montpellier HSC | 2:1 | ||||
| 14. Round | 06/11/1999 | ATAC Troyes | - | Montpellier HSC | 2:1 | ||||
| 15. Round | 09/11/1999 | Montpellier HSC | - | Stade Rennais | 1:2 | ||||
| 16. Round | 18/11/1999 | FC Metz | - | Montpellier HSC | 2:2 | ||||
| 17. Round | 26/11/1999 | Montpellier HSC | - | Paris Saint-Germain | 0:1 | ||||
| 18. Round | 02/12/1999 | Girondins Bordeaux | - | Montpellier HSC | 2:0 |
France