| 2. Round | 29/09/2020 | FC Bourg-Péronnas | - | FC Annecy | 1:0 |  |
|||
| 8. Round | 05/10/2020 | US Orléans | - | FC Annecy | 6:1 | ||||
| 9. Round | 09/10/2020 | US Avranches | - | FC Annecy | 1:3 | ||||
| 10. Round | 13/10/2020 | Stade Briochin | - | FC Annecy | 1:0 | ||||
| 13. Round | 14/11/2020 | FC Annecy | - | FC Bastia-Borgo | 1:1 | |
|||
| 3. Round | 20/11/2020 | FC Annecy | - | FC Villefranche Beaujolais | 1:0 | ||||
| 20. Round | 09/02/2021 | FC Annecy | - | FC Sète | 0:2 | ||||
| 21. Round | 23/02/2021 | US Concarneau | - | FC Annecy | 0:0 | ||||
| 23. Round | 27/02/2021 | US Créteil-Lusitanos | - | FC Annecy | 4:1 |  |
|||
| 26. Round | 19/03/2021 | FC Annecy | - | Stade Briochin | 1:1 | ||||
| 24. Round | 23/03/2021 | FC Annecy | - | US Orléans | 2:0 | ||||
| 27. Round | 27/03/2021 | Sporting Club Lyon | - | FC Annecy | 0:3 | ||||
| 28. Round | 02/04/2021 | FC Annecy | - | SO Cholet | 2:0 | |
|||
| 29. Round | 09/04/2021 | FC Bastia-Borgo | - | FC Annecy | 0:0 | ||||
| 30. Round | 19/04/2021 | US Quevilly-Rouen | - | FC Annecy | 1:1 |
France