| 3. Round | 22/08/2015 | OGC Nice | - | SM Caen | 2:1 | ||||
| 4. Round | 29/08/2015 | SM Caen | - | Olympique Lyonnais | 0:4 | ||||
| 5. Round | 12/09/2015 | ESTAC Troyes | - | SM Caen | 1:3 |  |
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| 7. Round | 23/09/2015 | FC Lorient | - | SM Caen | 2:0 |  |
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| 13. Round | 07/11/2015 | SM Caen | - | EA Guingamp | 2:1 | ||||
| 14. Round | 22/11/2015 | SM Caen | - | Angers SCO | 0:0 | ||||
| 15. Round | 29/11/2015 | Girondins Bordeaux | - | SM Caen | 1:4 | |
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| 16. Round | 02/12/2015 | AS Monaco | - | SM Caen | 1:1 | ||||
| 18. Round | 11/12/2015 | Stade Rennais | - | SM Caen | 1:1 | |
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| 19. Round | 19/12/2015 | SM Caen | - | Paris Saint-Germain | 0:3 | ||||
| 21. Round | 17/01/2016 | SM Caen | - | Olympique Marseille | 1:3 | ||||
| 22. Round | 23/01/2016 | Montpellier HSC | - | SM Caen | 1:2 | ||||
| 23. Round | 31/01/2016 | SM Caen | - | OGC Nice | 2:0 | ||||
| 24. Round | 03/02/2016 | Lille OSC | - | SM Caen | 1:0 | ||||
| 28. Round | 28/02/2016 | AS Saint-Étienne | - | SM Caen | 1:2 | ||||
| 35. Round | 24/04/2016 | EA Guingamp | - | SM Caen | 1:1 | ||||
| 36. Round | 30/04/2016 | SM Caen | - | SC Bastia | 0:0 | ||||
| 37. Round | 07/05/2016 | FC Nantes | - | SM Caen | 1:2 |
France