| 16. Round | 09/01/2022 | Real Sociedad [Women] | - | Athletic Club [Women] | 1:0 | ||||
| 17. Round | 12/01/2022 | Valencia CF [Women] | - | Real Sociedad [Women] | 0:3 | ||||
| 19. Round | 29/01/2022 | Villarreal CF [Women] | - | Real Sociedad [Women] | 1:4 | ||||
| 20. Round | 02/02/2022 | Real Sociedad [Women] | - | Real Madrid [Women] | 1:3 | ||||
| 21. Round | 06/02/2022 | Real Sociedad [Women] | - | Atlético Madrid [Women] | 2:2 | ||||
| 18. Round | 09/02/2022 | Real Sociedad [Women] | - | FC Barcelona [Women] | 1:9 | ||||
| 22. Round | 13/02/2022 | Levante UD [Women] | - | Real Sociedad [Women] | 1:0 | ||||
| 23. Round | 06/03/2022 | Real Sociedad [Women] | - | SD Eibar [Women] | 2:1 | ||||
| 24. Round | 12/03/2022 | Real Betis [Women] | - | Real Sociedad [Women] | 0:3 |  |
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| 25. Round | 27/03/2022 | Sporting de Huelva [Women] | - | Real Sociedad [Women] | 1:2 | ||||
| 26. Round | 02/04/2022 | Real Sociedad [Women] | - | Madrid CFF [Women] | 0:1 | ||||
| 27. Round | 16/04/2022 | Sevilla FC [Women] | - | Real Sociedad [Women] | 1:2 | ||||
| 28. Round | 01/05/2022 | Real Sociedad [Women] | - | Rayo Vallecano [Women] | 4:0 |
Norway