| 1. Round | 07/08/2021 | C'Chartres Football | - | US Granvillaise | 2:1 | ||||
| 2. Round | 14/08/2021 | US Granvillaise | - | Châteaubriant Voltigeurs | 0:0 |  |
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| 3. Round | 21/08/2021 | Vannes OC | - | US Granvillaise | 0:0 | ||||
| 4. Round | 28/08/2021 | SM Caen B | - | US Granvillaise | 1:1 | ||||
| 5. Round | 04/09/2021 | US Granvillaise | - | SO Romorantin | 1:2 | |
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| 6. Round | 11/09/2021 | FC Rouen 1899 | - | US Granvillaise | 0:2 | ||||
| 7. Round | 18/09/2021 | US Granvillaise | - | AS Vitré | 1:1 |  |
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| 8. Round | 25/09/2021 | FC Versailles | - | US Granvillaise | 0:0 | ||||
| 9. Round | 09/10/2021 | US Granvillaise | - | US Saint-Malo | 1:0 | ||||
| 10. Round | 23/10/2021 | Stade Plabennec | - | US Granvillaise | 3:1 | ||||
| 11. Round | 06/11/2021 | US Granvillaise | - | St-Pryvé St-Hilaire | 2:1 | ||||
| 12. Round | 20/11/2021 | Blois Foot 41 | - | US Granvillaise | 2:2 | ||||
| 13. Round | 04/12/2021 | US Granvillaise | - | FC Lorient B | 0:0 | ||||
| 14. Round | 11/12/2021 | EA Guingamp B | - | US Granvillaise | 1:0 | |
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| 15. Round | 15/01/2022 | US Granvillaise | - | AS Poissy | 2:2 | |
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| 28. Round | 14/05/2022 | US Granvillaise | - | EA Guingamp B | 3:4 |
France