| 16. Round | 06/02/2022 | Pau FC [Youth B] | - | Rodez AF [Youth B] | 0:1 | ||||
| 15. Round | 20/02/2022 | Montpellier HSC [Youth B] | - | Pau FC [Youth B] | 2:1 | ||||
| 19. Round | 13/03/2022 | Balma SC [Youth B] | - | Pau FC [Youth B] | 5:0 | ||||
| 20. Round | 20/03/2022 | Pau FC [Youth B] | - | Toulouse FC [Youth B] | 1:3 | ||||
| 21. Round | 27/03/2022 | AS Béziers [Youth B] | - | Pau FC [Youth B] | 2:0 | ||||
| 22. Round | 03/04/2022 | FC Istres [Youth B] | - | Pau FC [Youth B] | 5:2 | ||||
| 23. Round | 10/04/2022 | Pau FC [Youth B] | - | Marignane Gignac [Youth B] | 3:2 | ||||
| 24. Round | 17/04/2022 | SA Mérignac [Youth B] | - | Pau FC [Youth B] | 2:5 | ||||
| 25. Round | 01/05/2022 | Pau FC [Youth B] | - | AS Muret [Youth B] | 4:0 |
France