| 1. Round | 07/08/2021 | RC Lens B | - | FC Fleury 91 | 1:3 | ||||
| 3. Round | 21/08/2021 | RC Lens B | - | FC Metz B | 0:2 | ||||
| 4. Round | 28/08/2021 | SC Schiltigheim | - | RC Lens B | 1:0 | ||||
| 5. Round | 04/09/2021 | RC Lens B | - | Entente SSG | 1:0 |  |
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| 6. Round | 11/09/2021 | SAS Épinal | - | RC Lens B | 4:0 | ||||
| 9. Round | 09/10/2021 | RC Lens B | - | Stade de Reims B | 2:5 | ||||
| 10. Round | 23/10/2021 | AJ Auxerre B | - | RC Lens B | 1:1 | ||||
| 12. Round | 20/11/2021 | Paris 13 Atletico | - | RC Lens B | 0:0 | ||||
| 23. Round | 26/03/2022 | Stade de Reims B | - | RC Lens B | 0:3 | |
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| 27. Round | 30/04/2022 | FC 93 Bobigny | - | RC Lens B | 3:2 | ||||
| 29. Round | 21/05/2022 | RC Lens B | - | AS Beauvais | 2:2 | ||||
| 30. Round | 28/05/2022 | FC Fleury 91 | - | RC Lens B | 5:0 |
France