| 2. Round | 05/09/2021 | Nîmes Olympique [Youth B] | - | Pau FC [Youth B] | 2:2 | ||||
| 4. Round | 19/09/2021 | Rodez AF [Youth B] | - | Pau FC [Youth B] | 4:0 | ||||
| 5. Round | 25/09/2021 | Pau FC [Youth B] | - | Girondins Bordeaux [Youth B] | 2:3 | ||||
| 6. Round | 02/10/2021 | Montauban FC [Youth B] | - | Pau FC [Youth B] | 3:2 | ||||
| 7. Round | 10/10/2021 | Pau FC [Youth B] | - | Balma SC [Youth B] | 0:1 | ||||
| 8. Round | 17/10/2021 | Toulouse FC [Youth B] | - | Pau FC [Youth B] | 5:1 | ||||
| 10. Round | 14/11/2021 | Pau FC [Youth B] | - | FC Istres [Youth B] | 4:5 | ||||
| 11. Round | 21/11/2021 | Marignane Gignac [Youth B] | - | Pau FC [Youth B] | 2:1 | ||||
| 12. Round | 28/11/2021 | Pau FC [Youth B] | - | SA Mérignac [Youth B] | 1:1 | ||||
| 13. Round | 05/12/2021 | AS Muret [Youth B] | - | Pau FC [Youth B] | 0:3 | ||||
| 17. Round | 12/02/2022 | Girondins Bordeaux [Youth B] | - | Pau FC [Youth B] | 2:1 | ||||
| 19. Round | 13/03/2022 | Balma SC [Youth B] | - | Pau FC [Youth B] | 5:0 | ||||
| 22. Round | 03/04/2022 | FC Istres [Youth B] | - | Pau FC [Youth B] | 5:2 | ||||
| 23. Round | 10/04/2022 | Pau FC [Youth B] | - | Marignane Gignac [Youth B] | 3:2 |
France