| 3. Round | 15/06/2022 | Defensa y Justicia | - | Huracán | 1:1 | ||||
| 4. Round | 20/06/2022 | Godoy Cruz | - | Defensa y Justicia | 2:1 |  |
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| 5. Round | 25/06/2022 | Defensa y Justicia | - | Vélez Sarsfield | 1:1 | |
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| 6. Round | 03/07/2022 | Gimnasia de La Plata | - | Defensa y Justicia | 1:0 | |
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| 7. Round | 11/07/2022 | Defensa y Justicia | - | Aldosivi | 3:2 | ||||
| 8. Round | 15/07/2022 | Sarmiento de Junín | - | Defensa y Justicia | 2:0 | |
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| 9. Round | 20/07/2022 | Defensa y Justicia | - | Independiente | 2:1 | ||||
| 10. Round | 25/07/2022 | Newell's Old Boys | - | Defensa y Justicia | 1:2 | ||||
| 12. Round | 08/08/2022 | Central Córdoba SdE | - | Defensa y Justicia | 1:0 | ||||
| 14. Round | 18/08/2022 | Barracas Central | - | Defensa y Justicia | 3:1 | ||||
| 24. Round | 10/10/2022 | Rosario Central | - | Defensa y Justicia | 0:0 | ||||
| 25. Round | 14/10/2022 | Defensa y Justicia | - | Unión de Santa Fe | 1:0 | |
Argentina
Spain