| 2. Round | 10/06/2022 | Defensa y Justicia II | - | Lanús II | 1:0 | ||||
| 3. Round | 14/06/2022 | Huracán II | - | Defensa y Justicia II | 3:0 | ||||
| 4. Round | 20/06/2022 | Defensa y Justicia II | - | Godoy Cruz II | 1:0 | ||||
| 5. Round | 27/06/2022 | Vélez Sarsfield II | - | Defensa y Justicia II | 1:2 | ||||
| 6. Round | 01/07/2022 | Defensa y Justicia II | - | Gimnasia de La Plata II | 1:2 | ||||
| 11. Round | 31/07/2022 | Arsenal de Sarandí II | - | Defensa y Justicia II | 1:1 | ||||
| 12. Round | 05/08/2022 | Defensa y Justicia II | - | Central Córdoba SdE II | 1:0 | ||||
| 14. Round | 16/08/2022 | Defensa y Justicia II | - | Barracas Central II | 3:1 | ||||
| 16. Round | 28/08/2022 | Defensa y Justicia II | - | Banfield II | 1:2 | ||||
| 17. Round | 01/09/2022 | San Lorenzo II | - | Defensa y Justicia II | 1:0 | ||||
| 19. Round | 14/09/2022 | Argentinos Juniors II | - | Defensa y Justicia II | 0:0 | ||||
| 20. Round | 17/09/2022 | Defensa y Justicia II | - | Estudiantes II | 0:0 | ||||
| 21. Round | 22/09/2022 | Patronato de Paraná II | - | Defensa y Justicia II | 0:4 | ||||
| 23. Round | 03/10/2022 | Racing Club II | - | Defensa y Justicia II | 1:1 |
Argentina