| 1. Round | 29/09/1940 | Sevilla FC | - | FC Barcelona | 11:1 |  |
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| 2. Round | 06/10/1940 | Real Oviedo | - | Sevilla FC | 0:4 | |
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| 3. Round | 13/10/1940 | Sevilla FC | - | Valencia CF | 10:3 | |
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| 4. Round | 20/10/1940 | RC Celta | - | Sevilla FC | 2:2 | ||||
| 5. Round | 27/10/1940 | Sevilla FC | - | Real Zaragoza | 4:1 | |
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| 6. Round | 03/11/1940 | Real Murcia | - | Sevilla FC | 2:1 | ||||
| 7. Round | 10/11/1940 | Sevilla FC | - | Hércules CF | 8:3 | |
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| 8. Round | 17/11/1940 | Real Madrid | - | Sevilla FC | 4:1 | ||||
| 9. Round | 24/11/1940 | Sevilla FC | - | Atlético Aviación | 1:1 | ||||
| 11. Round | 08/12/1940 | Espanyol Barcelona | - | Sevilla FC | 4:3 | ||||
| 12. Round | 15/12/1940 | FC Barcelona | - | Sevilla FC | 4:0 | ||||
| 13. Round | 22/12/1940 | Sevilla FC | - | Real Oviedo | 4:1 | |
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| 14. Round | 29/12/1940 | Valencia CF | - | Sevilla FC | 4:1 | |
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| 15. Round | 05/01/1941 | Sevilla FC | - | RC Celta | 3:0 | |
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| 17. Round | 26/01/1941 | Sevilla FC | - | Real Murcia | 3:2 | |
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| 18. Round | 02/02/1941 | Hércules CF | - | Sevilla FC | 1:0 | ||||
| 22. Round | 02/03/1941 | Sevilla FC | - | Espanyol Barcelona | 3:1 |
Spain