| 3. Round | 28/08/2021 | Kocaelispor | - | Samsunspor | 1:0 | ||||
| 14. Round | 27/11/2021 | Kocaelispor | - | Menemen Belediyespor | 1:2 | ||||
| 15. Round | 05/12/2021 | Manisa FK | - | Kocaelispor | 2:1 |  |
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| 17. Round | 14/12/2021 | Altınordu FK | - | Kocaelispor | 3:2 | ||||
| 18. Round | 19/12/2021 | Kocaelispor | - | Eyüpspor | 1:1 | ||||
| 19. Round | 24/12/2021 | Adanaspor | - | Kocaelispor | 2:0 | ||||
| 20. Round | 08/01/2022 | Ümraniyespor | - | Kocaelispor | 1:0 | ||||
| 21. Round | 15/01/2022 | Kocaelispor | - | MKE Ankaragücü | 1:2 | ||||
| 22. Round | 21/01/2022 | Samsunspor | - | Kocaelispor | 3:0 | ||||
| 23. Round | 07/02/2022 | Kocaelispor | - | Boluspor | 1:2 | ||||
| 33. Round | 20/04/2022 | Menemen Belediyespor | - | Kocaelispor | 1:1 | ||||
| 34. Round | 24/04/2022 | Kocaelispor | - | Manisa FK | 2:1 | ||||
| 35. Round | 01/05/2022 | BB Erzurumspor | - | Kocaelispor | 1:0 | ||||
| 38. Round | 21/05/2022 | Kocaelispor | - | Adanaspor | 4:1 |  |
Turkey