| 1. Round | 12/08/2022 | USL Dunkerque | - | Le Mans FC | 3:0 |  |
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| 2. Round | 22/08/2022 | Le Mans FC | - | CS Sedan | 6:1 | ||||
| 4. Round | 05/09/2022 | Le Mans FC | - | Red Star FC | 0:0 | ||||
| 5. Round | 09/09/2022 | AS Nancy Lorraine | - | Le Mans FC | 2:0 | ||||
| 9. Round | 12/10/2022 | FC Versailles | - | Le Mans FC | 2:1 | ||||
| 10. Round | 21/10/2022 | Le Mans FC | - | FC Martigues | 1:1 | ||||
| 11. Round | 04/11/2022 | SO Cholet | - | Le Mans FC | 2:1 | ||||
| 12. Round | 11/11/2022 | Le Mans FC | - | Le Puy Foot 43 | 5:1 | ||||
| 13. Round | 28/11/2022 | LB Châteauroux | - | Le Mans FC | 0:3 | ||||
| 14. Round | 02/12/2022 | Le Mans FC | - | FC Bourg-Péronnas | 1:1 | ||||
| 17. Round | 13/01/2023 | Le Mans FC | - | FC Villefranche Beaujolais | 1:1 | ||||
| 24. Round | 10/03/2023 | US Avranches | - | Le Mans FC | 4:0 | ||||
| 26. Round | 27/03/2023 | FC Martigues | - | Le Mans FC | 3:1 | ||||
| 30. Round | 21/04/2023 | FC Bourg-Péronnas | - | Le Mans FC | 1:1 |  |
France