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| 1st(1st leg) | JS Kabylie | - | Espérance de Tunis | 0:1 (0:0) | ||
| 2nd (2nd leg) | Espérance de Tunis | - | JS Kabylie | 1:1 (0:0) | ||
| 1st(1st leg): 21/04/2023 22:00 | 2nd (2nd leg): 29/04/2023 20:00 | Winner: Espérance de Tunis | ||||
| 1st(1st leg) | Simba SC | - | Wydad AC | 1:0 (1:0) | ||
| 2nd (2nd leg) | Wydad AC | - | Simba SC | 4:3 (1:0, 1:0) pso | ||
| 1st(1st leg): 22/04/2023 19:00 | 2nd (2nd leg): 28/04/2023 20:00 | Winner: Wydad AC | ||||
| 1st(1st leg) | Al Ahly SC | - | Raja Casablanca | 2:0 (1:0) | ||
| 2nd (2nd leg) | Raja Casablanca | - | Al Ahly SC | 0:0 (0:0) | ||
| 1st(1st leg): 22/04/2023 20:00 | 2nd (2nd leg): 29/04/2023 20:00 | Winner: Al Ahly SC | ||||
| 1st(1st leg) | CR Bélouizdad | - | Mamelodi Sundowns | 1:4 (1:2) | ||
| 2nd (2nd leg) | Mamelodi Sundowns | - | CR Bélouizdad | 2:1 (1:1) | ||
| 1st(1st leg): 22/04/2023 20:00 | 2nd (2nd leg): 29/04/2023 14:00 | Winner: Mamelodi Sundowns | ||||
