 |
 |
|
| 1st(1st leg) | Club Nacional | - | Universitario de Deportes | 2:2 (0:0) | ||
| 2nd (2nd leg) | Universitario de Deportes | - | Club Nacional | 0:0 (0:0) | ||
| 1st(1st leg): 24/01/2006 | 2nd (2nd leg): 31/01/2006 | Winner: Universitario de Deportes | ||||
| 1st(1st leg) | Colo-Colo | - | Deportivo Guadalajara | 1:3 (0:1) | ||
| 2nd (2nd leg) | Deportivo Guadalajara | - | Colo-Colo | 5:3 (3:1) | ||
| 1st(1st leg): 24/01/2006 | 2nd (2nd leg): 31/01/2006 | Winner: Deportivo Guadalajara | ||||
| 1st(1st leg) | Palmeiras | - | Deportivo Táchira | 2:0 (1:0) | ||
| 2nd (2nd leg) | Deportivo Táchira | - | Palmeiras | 2:4 (0:3) | ||
| 1st(1st leg): 25/01/2006 | 2nd (2nd leg): 01/02/2006 | Winner: Palmeiras | ||||
| 1st(1st leg) | River Plate | - | Oriente Petrolero | 6:0 (4:0) | ||
| 2nd (2nd leg) | Oriente Petrolero | - | River Plate | 0:2 (0:2) | ||
| 1st(1st leg): 26/01/2006 | 2nd (2nd leg): 02/02/2006 | Winner: River Plate | ||||
| 1st(1st leg) | Deportivo Cuenca | - | Goiás - GO | 1:1 (0:1) | ||
| 2nd (2nd leg) | Goiás - GO | - | Deportivo Cuenca | 3:0 (1:0) | ||
| 1st(1st leg): 26/01/2006 | 2nd (2nd leg): 01/02/2006 | Winner: Goiás - GO | ||||
| 1st(1st leg) | Defensor Sporting | - | Santa Fe | 2:2 (0:1) | ||
| 2nd (2nd leg) | Santa Fe | - | Defensor Sporting | 0:0 (0:0) | ||
| 1st(1st leg): 27/01/2006 | 2nd (2nd leg): 02/02/2006 | Winner: Santa Fe | ||||
