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| 18/10/2022 | 15:30 | Levante Las Planas | - | Granada CF | 0:1 | |
| 19/10/2022 | 16:00 | Córdoba CF | - | Dux Logroño | 2:1 | |
| 17:00 | Fundación Tenerife | - | Deportivo La Coruña | 5:4 pso | ||
| 17:30 | Espanyol Barcelona | - | CP Cacereño | 2:0 | ||
| 19:00 | CE Europa | - | Real Oviedo | 1:3 | ||
| 19:00 | CD Juan Grande | - | CA Osasuna | 0:3 pso | ||
| 20/10/2022 | 16:00 | Elche CF | - | Alhama CF | 1:5 | |
| 16:30 | Friol | - | Fundación Albacete | 0:1 |
