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| 03/12/2022 | 13:30 | FC Nantes | - | USSA Vertou | 1:1 (0:0) | |
| 13:30 | USJA Carquefou | - | Stade Rennais | 1:0 (1:0) | ||
| 15:00 | EA Saint-Renan | - | EA Guingamp | 2:1 (1:0) | ||
| 15:00 | SO Cholet | - | FC Lorient | 6:1 (3:1) | ||
| 04/12/2022 | 10:00 | Angers SCO | - | Stade brestois 29 | 1:2 (0:1) | |
| 10:00 | Chamois Niortais | - | Vannes OC | 4:0 (3:0) | ||
| 13:30 | US Avranches | - | Le Mans FC | 1:3 (1:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Stade brestois 29 | 14 | 9 | 4 | 1 | 31:13 | 18 | 31 |
| 2 |
|
FC Nantes | 14 | 9 | 4 | 1 | 29:11 | 18 | 31 |
| 3 |
|
Angers SCO | 14 | 8 | 2 | 4 | 36:22 | 14 | 26 |
| 4 |
|
EA Guingamp | 14 | 8 | 2 | 4 | 28:18 | 10 | 26 |
| 5 |
|
Le Mans FC | 14 | 7 | 4 | 3 | 28:24 | 4 | 25 |
| 6 |
|
FC Lorient | 14 | 6 | 4 | 4 | 28:21 | 7 | 22 |
| 7 |
|
Stade Rennais | 14 | 7 | 0 | 7 | 20:24 | -4 | 21 |
| 8 |
|
SO Cholet | 14 | 5 | 3 | 6 | 33:29 | 4 | 18 |
| 9 |
|
USSA Vertou | 14 | 4 | 5 | 5 | 20:22 | -2 | 17 |
| 10 |
|
USJA Carquefou | 14 | 5 | 2 | 7 | 20:26 | -6 | 17 |
| 11 |
|
Chamois Niortais | 14 | 4 | 4 | 6 | 31:32 | -1 | 16 |
| 12 |
|
US Avranches | 14 | 4 | 0 | 10 | 21:32 | -11 | 12 |
| 13 |
|
EA Saint-Renan | 14 | 3 | 2 | 9 | 14:37 | -23 | 11 |
| 14 |
|
Vannes OC | 14 | 0 | 2 | 12 | 10:38 | -28 | 2 |
| Relegation |
