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| 09/11/2004 | 18:00 | Havre AC | - | Le Mans UC 72 | 4:1 (3:1) | |
| 18:00 | CS Sedan | - | AS Monaco | 0:1 (0:0) | ||
| 18:00 | Montpellier HSC | - | Stade de Reims | 3:1 (0:1) | ||
| 20:00 | Stade Brestois 29 | - | FC Sochaux | 1:2 (1:1) | ||
| 20:00 | OGC Nice | - | RC Lens | 4:5 (1:1, 1:1) pso | ||
| 20:00 | Dijon FCO | - | Girondins Bordeaux | 2:1 (1:0, 1:1) aet | ||
| 20:00 | ESTAC Troyes | - | RC Strasbourg | 1:3 (0:1) | ||
| 20:00 | AC Ajaccio | - | SM Caen | 0:2 (0:1) | ||
| 20:00 | Clermont Foot Auvergne | - | Toulouse FC | 5:4 (0:0, 0:0, 0:0) pso | ||
| 20:00 | AS Saint-Étienne | - | US Créteil-Lusitanos | 3:1 (1:0) | ||
| 20:00 | FC Metz | - | SC Bastia | 1:2 (0:0, 0:0) aet | ||
| 10/11/2004 | 15:05 | Stade Rennais | - | AJ Auxerre | 4:6 (0:0, 1:1, 1:1) pso | |
| 18:00 | Lille OSC | - | Olympique Lyonnais | 3:2 (0:0, 1:1) aet | ||
| 18:00 | FC Nantes | - | Stade Lavallois | 2:1 (0:1) | ||
| 18:00 | EA Guingamp | - | FC Istres | 4:2 (0:0, 1:1) aet | ||
| 20:00 | Olympique Marseille | - | Paris Saint-Germain | 2:3 (2:1) |
