| 1. Round | 03/06/2022 | Colón de Santa Fe II | - | Atlético Tucumán II | 2:2 | ||||
| 2. Round | 09/06/2022 | Atlético Tucumán II | - | River Plate II | 1:0 | ||||
| 3. Round | 14/06/2022 | Lanús II | - | Atlético Tucumán II | 2:4 | ||||
| 5. Round | 27/06/2022 | Godoy Cruz II | - | Atlético Tucumán II | 3:0 | ||||
| 6. Round | 03/07/2022 | Atlético Tucumán II | - | Vélez Sarsfield II | 1:0 | ||||
| 7. Round | 08/07/2022 | Gimnasia de La Plata II | - | Atlético Tucumán II | 1:1 | ||||
| 8. Round | 14/07/2022 | Atlético Tucumán II | - | Aldosivi II | 6:2 | ||||
| 9. Round | 18/07/2022 | Sarmiento de Junín II | - | Atlético Tucumán II | 2:0 | ||||
| 10. Round | 23/07/2022 | Atlético Tucumán II | - | Independiente II | 1:2 |  |
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| 11. Round | 28/07/2022 | Newell's Old Boys II | - | Atlético Tucumán II | 0:0 | ||||
| 15. Round | 21/08/2022 | Barracas Central II | - | Atlético Tucumán II | 2:0 | ||||
| 16. Round | 29/08/2022 | Atlético Tucumán II | - | Boca Juniors II | 1:2 | ||||
| 18. Round | 07/09/2022 | Atlético Tucumán II | - | San Lorenzo II | 1:2 | ||||
| 19. Round | 12/09/2022 | Talleres de Córdoba II | - | Atlético Tucumán II | 3:1 | ||||
| 20. Round | 19/09/2022 | Atlético Tucumán II | - | Argentinos Juniors II | 1:1 |
Argentina