| 22. Round | 02/01/2022 | CF Fuenlabrada | - | UD Ibiza | 1:2 | ||||
| 23. Round | 08/01/2022 | UD Ibiza | - | AD Alcorcón | 6:2 | ||||
| 24. Round | 22/01/2022 | Málaga CF | - | UD Ibiza | 0:5 | ||||
| 25. Round | 31/01/2022 | UD Ibiza | - | Real Zaragoza | 2:2 | ||||
| 26. Round | 04/02/2022 | UD Almería | - | UD Ibiza | 2:0 | ||||
| 27. Round | 12/02/2022 | UD Ibiza | - | FC Cartagena | 2:1 | ||||
| 28. Round | 19/02/2022 | CD Tenerife | - | UD Ibiza | 2:0 | ||||
| 38. Round | 01/05/2022 | Sporting Gijón | - | UD Ibiza | 0:1 | ||||
| 39. Round | 08/05/2022 | UD Ibiza | - | CD Lugo | 1:1 | ||||
| 42. Round | 29/05/2022 | Real Oviedo | - | UD Ibiza | 3:2 |
Spain