| 1. Round | 04/06/2022 | River Plate II | - | Defensa y Justicia II | 2:0 | ||||
| 5. Round | 27/06/2022 | Vélez Sarsfield II | - | Defensa y Justicia II | 1:2 | ||||
| 7. Round | 07/07/2022 | Aldosivi II | - | Defensa y Justicia II | 0:1 | ||||
| 8. Round | 13/07/2022 | Defensa y Justicia II | - | Sarmiento de Junín II | 3:1 | ||||
| 10. Round | 24/07/2022 | Defensa y Justicia II | - | Newell's Old Boys II | 1:2 | ||||
| 11. Round | 31/07/2022 | Arsenal de Sarandí II | - | Defensa y Justicia II | 1:1 | ||||
| 13. Round | 13/08/2022 | Tigre II | - | Defensa y Justicia II | 2:3 | ||||
| 21. Round | 22/09/2022 | Patronato de Paraná II | - | Defensa y Justicia II | 0:4 | ||||
| 23. Round | 03/10/2022 | Racing Club II | - | Defensa y Justicia II | 1:1 | ||||
| 24. Round | 07/10/2022 | Defensa y Justicia II | - | Rosario Central II | 0:6 | ||||
| 25. Round | 12/10/2022 | Unión de Santa Fe II | - | Defensa y Justicia II | 0:1 | ||||
| 26. Round | 17/10/2022 | Defensa y Justicia II | - | Colón de Santa Fe II | 0:1 | ||||
| 27. Round | 21/10/2022 | Atlético Tucumán II | - | Defensa y Justicia II | 1:0 |
Argentina