| 11. Round | 01/08/2022 | San Lorenzo II | - | Argentinos Juniors II | 3:4 | ||||
| 12. Round | 08/08/2022 | Estudiantes II | - | San Lorenzo II | 4:2 | ||||
| 13. Round | 12/08/2022 | San Lorenzo II | - | Patronato de Paraná II | 1:2 | ||||
| 14. Round | 17/08/2022 | Platense II | - | San Lorenzo II | 0:0 | ||||
| 15. Round | 23/08/2022 | San Lorenzo II | - | Racing Club II | 2:0 | ||||
| 16. Round | 28/08/2022 | Rosario Central II | - | San Lorenzo II | 0:1 | ||||
| 18. Round | 07/09/2022 | Atlético Tucumán II | - | San Lorenzo II | 1:2 | ||||
| 19. Round | 12/09/2022 | San Lorenzo II | - | Colón de Santa Fe II | 2:1 | ||||
| 20. Round | 19/09/2022 | River Plate II | - | San Lorenzo II | 1:0 | ||||
| 23. Round | 04/10/2022 | San Lorenzo II | - | Godoy Cruz II | 0:1 | ||||
| 24. Round | 10/10/2022 | Vélez Sarsfield II | - | San Lorenzo II | 2:0 | ||||
| 25. Round | 14/10/2022 | San Lorenzo II | - | Gimnasia de La Plata II | 3:1 | ||||
| 26. Round | 18/10/2022 | San Lorenzo II | - | Sarmiento de Junín II | 0:0 |
Argentina