| 2. Round | 14/08/2021 | Étoile FC | - | Jura Sud | 1:2 | ||||
| 4. Round | 28/08/2021 | Étoile FC | - | Marignane Gignac FC | 2:0 | ||||
| 5. Round | 04/09/2021 | Olympique Lyonnais B | - | Étoile FC | 3:0 |  |
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| 6. Round | 11/09/2021 | Étoile FC | - | RC Grasse | 2:2 | ||||
| 7. Round | 17/09/2021 | Louhans-Cuiseaux | - | Étoile FC | 0:0 | ||||
| 8. Round | 25/09/2021 | Étoile FC | - | Hyères FC | 0:0 | ||||
| 9. Round | 09/10/2021 | Lyon-La Duchère | - | Étoile FC | 0:1 | ||||
| 10. Round | 23/10/2021 | Étoile FC | - | AS Monaco B | 1:1 | |
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| 11. Round | 06/11/2021 | FC Martigues | - | Étoile FC | 0:3 | ||||
| 12. Round | 20/11/2021 | Étoile FC | - | GFA Rumilly Vallières | 1:0 | ||||
| 13. Round | 04/12/2021 | AS Saint-Priest | - | Étoile FC | 1:3 | ||||
| 1. Round | 18/12/2021 | Aubagne FC | - | Étoile FC | 2:1 | ||||
| 16. Round | 22/01/2022 | Jura Sud | - | Étoile FC | 1:0 | ||||
| 15. Round | 29/01/2022 | Étoile FC | - | GOAL FC | 0:0 | |
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| 18. Round | 12/02/2022 | Marignane Gignac FC | - | Étoile FC | 1:0 | ||||
| 22. Round | 19/03/2022 | Hyères FC | - | Étoile FC | 2:1 | ||||
| 27. Round | 30/04/2022 | Étoile FC | - | AS Saint-Priest | 0:0 | ||||
| 29. Round | 21/05/2022 | GOAL FC | - | Étoile FC | 0:1 | ||||
| 30. Round | 28/05/2022 | Étoile FC | - | Aubagne FC | 2:0 |
France