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| 19/03/2022 | 15:00 | AS Monaco (CFA) | - | GFA Rumilly Vallières | 2:2 (1:0) | |
| 15:00 | Olympique Lyon (CFA) | - | Jura Sud | 0:4 (0:2) | ||
| 17:00 | Hyères FC | - | Étoile FC | 2:1 (0:0) | ||
| 17:00 | FC Martigues | - | SC Toulon | 3:2 (1:1) | ||
| 17:00 | RC Grasse | - | Aubagne FC | 2:1 (0:0) | ||
| 17:00 | Louhans-Cuiseaux | - | GOAL FC | 0:0 (0:0) | ||
| 17:00 | Lyon-La Duchère | - | AS Saint-Priest | 2:3 (0:1) | ||
| 17:00 | Marignane Gignac FC | - | Olympique Marseille (CFA) | 4:1 (2:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
GOAL FC | 22 | 13 | 7 | 2 | 38:13 | 25 | 46 |
| 2 |
|
FC Martigues | 22 | 10 | 8 | 4 | 30:22 | 8 | 38 |
| 3 |
|
RC Grasse | 22 | 9 | 8 | 5 | 24:20 | 4 | 35 |
| 4 |
|
Aubagne FC | 22 | 9 | 7 | 6 | 29:21 | 8 | 34 |
| 5 |
|
Louhans-Cuiseaux | 22 | 8 | 8 | 6 | 26:20 | 6 | 32 |
| 6 |
|
Marignane Gignac FC | 22 | 9 | 5 | 8 | 24:20 | 4 | 32 |
| 7 |
|
Jura Sud | 22 | 9 | 5 | 8 | 30:29 | 1 | 32 |
| 8 |
|
Étoile FC | 22 | 8 | 7 | 7 | 23:20 | 3 | 31 |
| 9 |
|
Hyères FC | 22 | 7 | 8 | 7 | 23:24 | -1 | 29 |
| 10 |
|
Olympique Lyon (CFA) | 22 | 7 | 7 | 8 | 20:29 | -9 | 28 |
| 11 |
|
SC Toulon | 22 | 6 | 9 | 7 | 22:21 | 1 | 27 |
| 12 |
|
AS Monaco (CFA) | 22 | 6 | 7 | 9 | 23:29 | -6 | 25 |
| 13 |
|
Lyon-La Duchère | 22 | 5 | 8 | 9 | 24:29 | -5 | 23 |
| 14 |
|
AS Saint-Priest | 22 | 6 | 4 | 12 | 25:33 | -8 | 22 |
| 15 |
|
GFA Rumilly Vallières | 22 | 5 | 7 | 10 | 17:28 | -11 | 22 |
| 16 |
|
Olympique Marseille (CFA) | 22 | 5 | 3 | 14 | 21:41 | -20 | 18 |
| Promotion | |
| Relegation |
