| 1. Round | 03/06/2022 | Vélez Sarsfield II | - | Patronato de Paraná II | 2:1 | ||||
| 7. Round | 11/07/2022 | Vélez Sarsfield II | - | Colón de Santa Fe II | 4:0 | ||||
| 10. Round | 25/07/2022 | Huracán II | - | Vélez Sarsfield II | 1:0 | ||||
| 11. Round | 30/07/2022 | Vélez Sarsfield II | - | Godoy Cruz II | 5:0 | ||||
| 12. Round | 05/08/2022 | Vélez Sarsfield II | - | Unión de Santa Fe II | 0:0 | ||||
| 14. Round | 16/08/2022 | Vélez Sarsfield II | - | Aldosivi II | 2:1 |  |
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| 15. Round | 20/08/2022 | Sarmiento de Junín II | - | Vélez Sarsfield II | 0:2 | ||||
| 16. Round | 26/08/2022 | Vélez Sarsfield II | - | Independiente II | 0:1 | ||||
| 17. Round | 31/08/2022 | Newell's Old Boys II | - | Vélez Sarsfield II | 0:2 | ||||
| 18. Round | 07/09/2022 | Vélez Sarsfield II | - | Arsenal de Sarandí II | 1:0 | ||||
| 19. Round | 14/09/2022 | Central Córdoba SdE II | - | Vélez Sarsfield II | 0:1 | ||||
| 21. Round | 24/09/2022 | Barracas Central II | - | Vélez Sarsfield II | 3:2 | ||||
| 22. Round | 30/09/2022 | Vélez Sarsfield II | - | Boca Juniors II | 2:1 | ||||
| 23. Round | 05/10/2022 | Banfield II | - | Vélez Sarsfield II | 1:3 | ||||
| 27. Round | 21/10/2022 | Vélez Sarsfield II | - | Argentinos Juniors II | 3:0 |
Argentina